Invitrogen™ Iduronate 2 Sulfatase Polyclonal Antibody

Catalog No.	Quantity
PIPA519035	100 μg

Catalog No. PIPA519035 Supplier Invitrogen™ Supplier No. PA519035

Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Specifications

• Antigen: Iduronate 2 Sulfatase
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: Ids
• Gene Accession No.: P22304
• Gene Alias: alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS
• Gene Symbols: Ids
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (KHFRFRDLEEDP) corresponding to the internal amino acids of IDS (aa 440-452).
• Purification Method: Ammonium Sulfate Precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3423
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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