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Iduronate 2 sulfatase Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983866
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50-198-3866 100 μL
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Catalog No. 50-198-3866 Supplier Bioss Supplier No. BS15543R
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Description

Rabbit Polyclonal Antibody

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Specifications

Antigen Iduronate 2 sulfatase
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Ids
Gene Accession No. P22304
Gene Alias Alpha-L-iduronate sulfate sulfatase; AW214631; BOS_25334; IDS; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); Iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; Idursulfase; MPS2; SIDS
Gene Symbols Ids
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Iduronate 2 sulfatase.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3423
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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