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  5. Tocris Bioscience™ IEM 1925 dihydrobromide

Tocris Bioscience™ IEM 1925 dihydrobromide

Catalog No. 419810
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Catalog No. Quantity
41-981-0 10 mg
41-985-0 50 mg
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Catalog No. 41-981-0 Supplier Tocris Bioscience™ Supplier No. 4198/10
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Description

Voltage- and use-dependent open-channel antagonist of AMPA receptors

IEM 1925 dihydrobromide is a voltage- and use-dependent open-channel antagonist of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking receptors more potently than GluA2-containing receptors (KD for GluA2-containing AMPAR is 210 times higher at -80 mV). More potent than IEM 1460 (Cat. No. 1636) and IEM 1754 due to a slower unblocking rate. Alleviates inflammatory pain in a rat model of peripheral inflammation.

Chemical Identifiers

CAS 258282-23-4
Molecular Formula C17H30Br2N2

Specifications

Quantity 10 mg
Formula Weight 422.24
Purity 95%
Molecular Weight (g/mol) 422.249
Chemical Name or Material IEM 1925 dihydrobromide

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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