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Invitrogen™ IFI6 Polyclonal Antibody
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Catalog No. PIPA576860
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100 μL
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PIPA576860 100 μL
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Catalog No. PIPA576860 Supplier Invitrogen™ Supplier No. PA576860
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130 amino acid member of the IFI6 family of proteins. Localized to the mitochondria, G1P3 is a multi-pass membrane protein that is induced by IFN-α2β. G1P3 has been shown to play a major role in the apoptosis pathway. Specifically, G1P3 acts as a cell survival protein by inhibiting caspase-3 activity, which antagonizes apoptosis. G1P3 has been implicated in tumorigenesis and is the subject of therapeutic studies, as reducing G1P3-mediated antiapoptotic signals could suggest improved therapies for myeloma or other malignancies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFI6
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene IFI6
Gene Accession No. P09912
Gene Alias 6-16; FAM14C; G1P3; IFI6; IFI616; IFI-6-16; interferon alpha inducible protein 6; interferon alpha-inducible protein 6; interferon, alpha-inducible protein 6; interferon, alpha-inducible protein clone IFI-6-16; interferon-induced protein 6-16
Gene Symbols IFI6
Host Species Rabbit
Immunogen Recombinant full length Human IFI6.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2537
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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