IFIH1 Mouse anti-Human, Clone: OTI8C10, lyophilized, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene CF803667

Catalog No. 50-166-6618

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Melanoma differentiation associated gene 5, MDA5, is a pattern recognition receptor to transmit the signal.Once activated, both proteins signal through IPS-1 activating transcription factors NF- kappaB and IRF-3 and ultimately activating apoptosis, cytokine signaling, and inflammation. RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus, paromyxoviruses, Japanese encephalitis virus. MDA5 is essential for signaling by picornavirus. Both RIG-I and MDA5 are responsible for signaling by West Nile virus.

Specifications

• Antigen: IFIH1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: IFIH1
• Format: Lyophilized
• Gene Symbols: IFIH1
• Immunogen: Full length human recombit protein of human IFIH1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: Western Blot
• Clone: OTI8C10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9BYX4
• Gene Alias: AGS7, Hlcd, IDDM19, MDA-5, MDA5, RLR-2, SGMRT1
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μg
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 64135