Invitrogen™ IFITM2 Monoclonal Antibody (OTI4E3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527504

Catalog No. PIMA527504

Description

IFITM2 Monoclonal Antibody for Western Blot, IHC (P)

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Specifications

• Antigen: IFITM2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q01629
• Gene Symbols: IFITM2
• Immunogen: Full length human recombinant protein of IFITM2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4E3
• Conjugate: Unconjugated
• Gene: IFITM2
• Gene Alias: 1-8D; dispanin subfamily A member 2c; DSPA2c; IFITM2; ifm2; interferon induced transmembrane protein 2; interferon-induced transmembrane protein 2; Interferon-inducible protein 1-8D
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10581
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid