IFITM2 Mouse anti-Human, Clone: OTI2B3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527502
DescriptionIFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|1-8D, interferon-induced transmembrane protein 2, interferon-inducible protein 1-8D|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of IFITM2 produced in E.coli|
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