Invitrogen™ IFITM3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597857

Catalog No. PIPA597857

Description

IFITM3 Polyclonal Antibody for Western Blot, IHC (P), IP, ELISA

IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-alpha and IFN-gamma. IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.

Specifications

• Antigen: IFITM3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IFITM3
• Gene Alias: 1110004C05Rik; 1-8U; Cd225; Cdw217; Dispanin subfamily A member 2b; DSPA2b; Fgls; Fragilis; Fragilis 3; Fragilis protein; Ifitm3; ifitm-like protein 1; interferon induced transmembrane protein 3; interferon-induced transmembrane protein 3; interferon-inducible protein 15; Interferon-inducible protein 1-8U; interferon-inducible protein variant 10; IP15; mil-1; Mouse ifitm-like protein 1; rat8
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10410
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 3.545 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q01628
• Gene Symbols: IFITM3
• Immunogen: Recombinant Human Interferon-induced transmembrane protein 3 protein (1-57AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov