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IFN beta Polyclonal Antibody, Invitrogen™

Catalog No. PIPA595722
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100 μL
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PIPA595722 100 μL
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Catalog No. PIPA595722 Supplier Thermo Scientific Supplier No. PA595722

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LQRSSNFQCQ KLLWQLNGRL EYCLKDRMNF DIPEEIKQLQ QFQKEDAALT IYEMLQNIFA IFRQDSSSTG WNETIVENLL ANVYHQINHL KTVLEEKLEK EDFTRGKLMS SLHLKRYYGR ILHYLKAKEY SHCAWTIVRV EILRNFYFIN RLTGYLRN; Positive Samples: A-549, A-431, Mouse liver, Mouse small intestine

Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFN beta
Applications Western Blot
Classification Polyclonal
Concentration 3.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Ifnb1
Gene Accession No. P01574, P01575
Gene Alias Fibroblast interferon, Ifb, IFF, IFN b, IFN β, IFNB, Ifnb1, IFNbeta, IFN-beta, IFNβ, Interferon b, Interferon beta, interferon beta 1, interferon beta 1, fibroblast, interferon beta protein, interferon, beta 1, interferon, beta 1, fibroblast, interferon-beta, RP11-113D19.1
Gene Symbols Ifnb1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-187 of human IFNB1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15977, 3456
Target Species Human, Mouse
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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