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  6. Invitrogen™ IFNAR1 Monoclonal Antibody (C7)

Invitrogen™ IFNAR1 Monoclonal Antibody (C7)

Catalog No. PIMA543696
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200 μL
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PIMA543696 20 μL
PIMA541609 200 μL
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Catalog No. PIMA543696 Supplier Invitrogen™ Supplier No. MA543696
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Description

Mouse Monoclonal Antibody

IFNAR1 Monoclonal Antibody for Western Blot

Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFNAR1
Applications Western Blot
Classification Monoclonal
Clone C7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene Ifnar1
Gene Accession No. P17181, Q764M8
Gene Alias alpha-type antiviral protein; AVP; beta-type antiviral protein; CD118; CRF2-1; cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; H3K1; Ifar; IFN R1; IFNalpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha/betaR; IFNalpha/betaR1; IFN-alpha/betaR1; IFN-alpha/betaRalpha; IFNalpha/beta-Ralpha; IFN-alpha-REC; IFNAR; Ifnar1; IFNBR; IFNR1; IFN-R-1; Ifrc; INF-a receptor; Infar; interferon (alpha and beta) receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha and beta receptor subunit 1; interferon alpha/beta receptor 1; interferon receptor 1; interferon-alpha/beta receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
Gene Symbols Ifnar1
Host Species Mouse
Immunogen Recombinant protein Interferon Alpha/Beta Receptor 1. The antigen corresponds to amino acid range 28-227 of the target protein.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 106508630, 288264, 3454, 396658
Target Species Human, Rat, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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