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IFNAR1 Recombinant Rabbit Monoclonal Antibody (110), PE, Invitrogen™

Catalog No. PIMA546832
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100 Tests
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PIMA546832 100 Tests
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Catalog No. PIMA546832 Supplier Thermo Scientific Supplier No. MA546832

Description

Rabbit Recombinant Monoclonal Antibody

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IFNAR1 (Met1-Thr429) and conjugated with PE under optimum conditions, the unreacted PE was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFNAR1
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 110
Concentration 100 μg/mL
Conjugate PE
Formulation PBS with 0.5% BSA and 0.09% sodium azide
Gene Ifnar1
Gene Accession No. P33896
Gene Alias alpha-type antiviral protein; AVP; beta-type antiviral protein; CD118; CRF2-1; cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; H3K1; Ifar; IFN R1; IFNalpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha/betaR; IFNalpha/betaR1; IFN-alpha/betaR1; IFN-alpha/betaRalpha; IFNalpha/beta-Ralpha; IFN-alpha-REC; IFNAR; Ifnar1; IFNBR; IFNR1; IFN-R-1; Ifrc; INF-a receptor; Infar; interferon (alpha and beta) receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha and beta receptor subunit 1; interferon alpha/beta receptor 1; interferon receptor 1; interferon-alpha/beta receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
Gene Symbols Ifnar1
Host Species Rabbit
Immunogen Recombinant protein encoding Mouse IFNAR1 (Met1-Thr429).
Purification Method Protein A
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15975
Target Species Mouse
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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