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Invitrogen™ IFNAR2 Polyclonal Antibody
Chicken Polyclonal Antibody
Supplier: Invitrogen™ PA19544
Description
PA1-9544 detects IFNAR2 in human samples. PA1-9544 has been successfully used in Western blot procedures. PA1-9544 immunogen is a purified recombinant IFNAR2 corresponding to the chromosome 21 gene (Human).
The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.
Specifications
IFNAR2 | |
Polyclonal | |
Unconjugated | |
IFNAR2 | |
AI747302; human interferon alpha/beta receptor; IFN alpha/betaRbeta; IFN R2; IFNABR; IFNalpha/beta R2; IFN-alpha/beta receptor 2; IFNalpha/betaR2; IFN-alpha/betaR2; IFN-alpha/betaRbeta; IFNalpha/beta-Rbeta; IFN-alpha-REC; IFNAR2; Ifnar-2; IFNARB; IFN-R; IFNR2; IFN-R-2; IMD45; interferon (alpha and beta) receptor 2; interferon (alpha, beta and omega) receptor 2; interferon alpha and beta receptor subunit 2; interferon alpha binding protein; Interferon alpha/beta receptor 2; interferon receptor 2c; interferon-alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; type I interferon alpha/beta receptor 2a; type I interferon receptor 2 | |
Chicken | |
IgY fraction | |
RUO | |
3455 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
P48551 | |
IFNAR2 | |
Purified recombinant IFNAR2 corresponding to the chromosome 21 gene (Human). | |
500 μg | |
Primary | |
Human | |
Antibody | |
IgY |
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