IFNAR2 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-6375	150 μL

Catalog No. 50-172-6375 Supplier Proteintech Group Inc Supplier No. 105221AP150UL

Description

Rabbit Polyclonal Antibody

The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.

Specifications

• Antigen: IFNAR2
• Applications: Flow Cytometry, Western Blot
• Classification: Polyclonal
• Concentration: 0.15 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: IFNAR2
• Gene Accession No.: P48551
• Gene Alias: IFN alpha REC, IFN alpha/beta receptor 2, IFN R, IFN R 2, IFNABR, IFNAR2, IFNARB, Type I interferon receptor 2
• Gene Symbols: IFNAR2
• Host Species: Rabbit
• Immunogen: IFNAR2 Fusion Protein Ag0191
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3455
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG