Invitrogen™ IFNAR2 Recombinant Rabbit Monoclonal Antibody (122), APC

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA540952

Catalog No. PIMA540952

Description

May be stored for twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze. Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal.

The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.

Specifications

• Antigen: IFNAR2
• Classification: Recombinant Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.5% BSA and 0.03% ProClin 300
• Gene Accession No.: P48551
• Gene Symbols: IFNAR2
• Immunogen: Recombinant Human IFNAR2 Protein.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry
• Clone: 122
• Conjugate: APC
• Gene: IFNAR2
• Gene Alias: AI747302; human interferon alpha/beta receptor; IFN alpha/betaRbeta; IFN R2; IFNABR; IFNalpha/beta R2; IFN-alpha/beta receptor 2; IFNalpha/betaR2; IFN-alpha/betaR2; IFN-alpha/betaRbeta; IFNalpha/beta-Rbeta; IFN-alpha-REC; IFNAR2; Ifnar-2; IFNARB; IFN-R; IFNR2; IFN-R-2; IMD45; interferon (alpha and beta) receptor 2; interferon (alpha, beta and omega) receptor 2; interferon alpha and beta receptor subunit 2; interferon alpha binding protein; Interferon alpha/beta receptor 2; interferon receptor 2c; interferon-alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; type I interferon alpha/beta receptor 2a; type I interferon receptor 2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3455
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov