Invitrogen™ IFNGR2 Polyclonal Antibody

Catalog No.	Quantity
PIPA547089	100 μg

Catalog No. PIPA547089 Supplier Invitrogen™ Supplier No. PA547089

Description

Goat Polyclonal Antibody

In Western blots, approximately 5% cross-reactivity with recombinant human IFN-gamma R2 is observed and less than 1% cross-reactivity with recombinant mouse (rm) IFN- gamma R1 and rmIFN-alpha / beta R2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.

Specifications

• Antigen: IFNGR2
• Applications: Neutralization, Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: IFNGR2
• Gene Accession No.: 0
• Gene Alias: AF-1; Ifgr2; Ifgt; IFN-gamma receptor 2; IFN-gamma-R2; IFN-gamma-R-beta; IFNGR2; IFNGT1; IMD28; Interferon gamma receptor 2; interferon gamma receptor 2 (interferon gamma transducer 1); interferon gamma receptor accessory factor 1; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma receptor beta-chain; Interferon gamma transducer 1
• Gene Symbols: IFNGR2
• Host Species: Goat
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IFN- gamma R2 Ser21-Val243.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 15980
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG