Invitrogen™ IFRD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577216

Catalog No. PIPA577216

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Tis7, also known as IFRD1, is a 442 amino acid containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family. A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase dependent manner.

Specifications

• Antigen: IFRD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IFRD1
• Gene Alias: 12-O-tetradecanoylphorbol-13-acetate-induced sequence 7; hypothetical protein LOC541283; Ifnl; Ifrd1; interferon related developmental regulator 1; interferon-related developmental regulator 1; IRPR; nerve growth factor-inducible protein PC4; Pc4; pheochromocytoma cell-4; Tis7; TIS7 protein; TPA induced sequence 7; TPA-induced sequence 7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15982, 29596, 3475
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O00458, P19182, P20695
• Gene Symbols: IFRD1
• Immunogen: Recombinant full length Human IFRD1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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