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Invitrogen™ IFRD1 Polyclonal Antibody
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Catalog No. PIPA5121100
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100 μL
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PIPA5121100 100 μL
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Catalog No. PIPA5121100 Supplier Invitrogen™ Supplier No. PA5121100
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Description

Rabbit Polyclonal Antibody

Positive test controls include: SW480, BT-474, HeLa, Raji, Mouse lung, Mouse skeletal muscle, Mouse spinal cord, Rat brain. Immunogen sequence: MPKNKKRNTP HRGSSAGGGG SGAAAATAAT AGGQHRNVQP FSDEDASIET MSHCSGYSDP SSFAEDGPEV LDEEGTQEDL EYKLKGLIDL TLDKSAKTRQ AALEGIKNAL ASKMLYEFIL ERRMTLTDSI ERCLKKGKSD EQRAAAALAS VLCIQLGPGI ESEEILKTLG PILKKIICDG SASMQARQTC ATCFGVCCFI ATDDITELYS TLECLENIFT KSYLKEKDTT VICSTPNTVL.

Tis7, also known as IFRD1, is a 442 amino acid containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family. A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFRD1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.64 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IFRD1
Gene Accession No. O00458, P19182, P20695
Gene Alias 12-O-tetradecanoylphorbol-13-acetate-induced sequence 7; hypothetical protein LOC541283; Ifnl; Ifrd1; interferon related developmental regulator 1; interferon-related developmental regulator 1; IRPR; nerve growth factor-inducible protein PC4; Pc4; pheochromocytoma cell-4; Tis7; TIS7 protein; TPA induced sequence 7; TPA-induced sequence 7
Gene Symbols IFRD1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human IFRD1 (NP_001541.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15982, 29596, 3475
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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