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IFRD1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728361 Shop All Proteintech Group Inc Products
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50-172-8361 150 μL
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Catalog No. 50-172-8361 Supplier Proteintech Group Inc Supplier No. 129391AP150UL
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Rabbit Polyclonal Antibody

Tis7, also known as IFRD1, is a 442 amino acid containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family. A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintece, and regeneration in a histone deacetylase dependent manner.

Specifications

Antigen IFRD1
Applications Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IFRD1
Gene Accession No. O00458, P19182, P20695
Gene Alias IFRD1, PC4, TIS7
Gene Symbols IFRD1
Host Species Rabbit
Immunogen IFRD1 Fusion Protein Ag3988
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15982, 29596, 3475
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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