Invitrogen™ IFT25 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100040

Catalog No. PIPA5100040

Description

Antibody detects endogenous levels of total IFT25.

HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.

Specifications

• Antigen: IFT25
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hspb11
• Gene Alias: 2900042B11Rik; C1orf41; Heat shock protein; Heat shock protein beta-11; heat shock protein family B (small) member 11; heat shock protein family B (small), member 11; HSP; Hspb11; Hspb11 heat shock protein family B (small), member 11; HSPC034; HSPCO34; IFT25; intraflagellar transport 25 homolog; intraflagellar transport protein 25 homolog; Placental protein 25; placental protein 25 homolog; PP25
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51668, 685284, 72938
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9D6H2, Q9Y547
• Gene Symbols: Hspb11
• Immunogen: A synthesized peptide derived from human HSPB11(Accession Q9Y547), corresponding to amino acid residues C7-V57.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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