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Invitrogen™ IFT25 Polyclonal Antibody
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Catalog No. PIPA5100040
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100 μL
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PIPA5100040 100 μL
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Catalog No. PIPA5100040 Supplier Invitrogen™ Supplier No. PA5100040
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IFT25.

HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFT25
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Hspb11
Gene Accession No. Q9D6H2, Q9Y547
Gene Alias 2900042B11Rik; C1orf41; Heat shock protein; Heat shock protein beta-11; heat shock protein family B (small) member 11; heat shock protein family B (small), member 11; HSP; Hspb11; Hspb11 heat shock protein family B (small), member 11; HSPC034; HSPCO34; IFT25; intraflagellar transport 25 homolog; intraflagellar transport protein 25 homolog; Placental protein 25; placental protein 25 homolog; PP25
Gene Symbols Hspb11
Host Species Rabbit
Immunogen A synthesized peptide derived from human HSPB11(Accession Q9Y547), corresponding to amino acid residues C7-V57.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51668, 685284, 72938
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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