IFT57 Monoclonal Antibody (OTI5B6), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-2049	100 μL
50-254-2696	30 μL

Catalog No. 50-167-2049 Supplier OriGene Supplier No. TA500906

Description

Mouse Monoclonal Antibody

HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5′-AAAGACATG-3′ present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Specifications

• Antigen: IFT57
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI5B6
• Concentration: 0.53 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: IFT57
• Gene Accession No.: Q9NWB7
• Gene Alias: ESRRBL1, HIPPI, MHS4R2
• Gene Symbols: IFT57
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human IFT57 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55081
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1