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IFT57 Mouse anti-Human, Clone: OTI4F6, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA500918

Catalog No. 50-167-2059


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Description

Description

HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5 ft.-AAAGACATG-3 ft. present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Specifications

Specifications

IFT57
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9NWB7
ESRRBL1, HIPPI, MHS4R2
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
55081
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI4F6
Unconjugated
IFT57
Liquid
IFT57
Full length human recombit protein of human IFT57 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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