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IFT57 Mouse anti-Human, Clone: OTI4F6, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA500918

Encompass_Preferred

Catalog No. 50-167-2059


May include imposed supplier surcharges.
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Description

Description

HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5′-AAAGACATG-3′ present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Specifications

Specifications

IFT57
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9NWB7
IFT57
Full length human recombit protein of human IFT57 produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI4F6
Unconjugated
IFT57
ESRRBL1, HIPPI, MHS4R2
Mouse
Affinity Chromatography
RUO
55081
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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