IFT57 Mouse anti-Human, Clone: OTI4F6, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA500918

Catalog No. 50-167-2059

Description

HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5′-AAAGACATG-3′ present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Specifications

• Antigen: IFT57
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9NWB7
• Gene Symbols: IFT57
• Immunogen: Full length human recombit protein of human IFT57 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4F6
• Conjugate: Unconjugated
• Gene: IFT57
• Gene Alias: ESRRBL1, HIPPI, MHS4R2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55081
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid