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Invitrogen™ IGF1R alpha Monoclonal Antibody (2C8)
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Catalog No. 01671868
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100 μg
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Catalog No. Quantity
01-671-868 100 μg
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Catalog No. 01-671-868 Supplier Invitrogen™ Supplier No. MA110855
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Description

Mouse Monoclonal Antibody

MA1-10855 detects IGF-1 Receptor from human samples. MA1-10855 has been successfully used in Western blot applications. The MA1-10855 immunogen is purified human placental IGF-1 receptors.

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of malignant cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGF1R alpha
Applications Western Blot
Classification Monoclonal
Clone 2C8
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Igf1r
Gene Accession No. P08069
Gene Alias A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Gene Symbols Igf1r
Host Species Mouse
Immunogen Purified human placental IGF-1 receptors.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3480
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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