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IGF1R beta chain Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 202541AP

Catalog No. 50-173-2797


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Description

Description

This antibody raised against a synthesized polypeptide (CGVLVLRASFDERQPYAH) corresponding to 1332-1348aa of human IGF1R protein recognizes beta subunit of IGF1R.

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of maligt cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.
Specifications

Specifications

IGF1R beta chain
0.22 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08069, P24062, Q60751
CD221, IGF I receptor, IGF1R, IGFIR, IGFR, JTK13
Rabbit
IgG
150 μL
-20°C
Primary
16001, 25718, 3480
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
IGF1R
Liquid
IGF1R
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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