IGF1R (phospho Y1161) Rabbit anti-Human, Mouse, Rabbit, Polyclonal , Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.

Supplier:  Abnova Corporation PAB29601

Catalog No. 89-956-756

Description

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq]

Specifications

• Antigen: IGF1R (phospho Y1161)
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Symbols: IGF1R
• Immunogen: A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1161 of human IGF1R.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: IGF1R (phospho Y1161) polyclonal antibody detects endogenous level of IGF1R only when phosphorylated at tyrosine 1161.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunofluorescence (1:100-1:200) Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene Alias: CD221/IGFIR/JTK13/MGC142170/MGC142172/MGC18216
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3480
• Target Species: Human, Mouse, Rabbit
• Form: Liquid