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IGF1R (phospho Y1161) Rabbit anti-Human, Mouse, Rabbit, Polyclonal , Abnova™

Catalog No. 89956756 Shop All Abnova Corporation Products
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89-956-756 100 μL
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Catalog No. 89-956-756 Supplier Abnova Corporation Supplier No. PAB29601
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq]

Specifications

Antigen IGF1R (phospho Y1161)
Applications Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.
Dilution Immunofluorescence (1:100-1:200) Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene Alias CD221/IGFIR/JTK13/MGC142170/MGC142172/MGC18216
Gene Symbols IGF1R
Host Species Rabbit
Immunogen A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1161 of human IGF1R.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3480
Test Specificity IGF1R (phospho Y1161) polyclonal antibody detects endogenous level of IGF1R only when phosphorylated at tyrosine 1161.
Target Species Human, Mouse, Rabbit
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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