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Invitrogen™ IGF2BP2 Polyclonal Antibody
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Catalog No. PIPA595923
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100 μL
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PIPA595923 100 μL
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Catalog No. PIPA595923 Supplier Invitrogen™ Supplier No. PA595923
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TVEACASAEI EIMKKLREAF ENDMLAVNQQ ANLIPGLNLS ALGIFSTGLS VLSPPAGPRG APPAAPYHPF TTHSGYFSSL YPHHQFGPFP HHHSYPEQEI VNLFIPTQAV GAIIGKKGAH IKQLARFAGA SIKIAPAEGP DVSERMVIIT GPPEAQFKAQ GRIFGKLKEE NFFNPKEEVK LEAHIRVPSS TAGRVIGKGG KTVNELQNLT SAEVIVPRDQ TPDENEEVIV RIIGHFFASQ TAQRKIREIV QQVKQQEQKY PQGVASQRSK; Positive Samples: HT-29, BxPC-3, HeLa, Jurkat, NIH3T3; Cellular Location: Cytoplasm, Nucleus.

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGF2BP2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene IGF2BP2
Gene Accession No. Q5SF07, Q9Y6M1
Gene Alias C330012H03Rik; Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF2BP2; IGF-II mRNA-binding protein 2; Imp2; IMP-2; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; Neilsen; p62; RGD1305614; VICKZ family member 2; VICKZ2
Gene Symbols IGF2BP2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 330-599 of human IGF2BP2/IMP2 (NP_0065393).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10644, 303824, 319765
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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