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IGF2BP2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501564826
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50-156-4826 100 μL
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Catalog No. 50-156-4826 Supplier Bethyl Laboratories, Inc Supplier No. A303317A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5′ UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.

Specifications

Antigen IGF2BP2
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene IGF2BP2
Gene Accession No. Q9Y6M1
Gene Alias IGF2BP2; insulin-like growth factor 2 mRNA binding protein 2; IMP-2; IMP2; VICKZ2; p62; IGF II mRNA binding protein 2; IGF-II mRNA-binding protein 2
Gene Symbols IGF2BP2
Host Species Rabbit
Immunogen Between 549 and 599
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10644
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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