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Invitrogen™ IGF2BP2 Recombinant Rabbit Monoclonal Antibody (1H13L3)

Catalog No. 703102
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Catalog No. Quantity
70-310-2 100 μg
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Catalog No. 70-310-2 Supplier Invitrogen™ Supplier No. 703102
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Pig, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGF2BP2
Applications Immunocytochemistry
Classification Recombinant Monoclonal
Clone 1H13L3
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene IGF2BP2
Gene Accession No. Q9Y6M1
Gene Alias C330012H03Rik; Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF2BP2; IGF-II mRNA-binding protein 2; Imp2; IMP-2; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; Neilsen; p62; RGD1305614; VICKZ family member 2; VICKZ2
Gene Symbols IGF2BP2
Host Species Rabbit
Immunogen Peptides corresponding to human IGF2BP2 [1) aa17-aa32 2) aa583-aa599].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10644
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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