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Invitrogen™ IGF2BP2 Recombinant Rabbit Monoclonal Antibody (2O3W8)
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Catalog No. PIMA542874
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100 μL
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PIMA542874 100 μL
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Catalog No. PIMA542874 Supplier Invitrogen™ Supplier No. MA542874
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HT-29, 293T, HepG2. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: NFFNPKEEVK LEAHIRVPSS TAGRVIGKGG KTVNELQNLT SAEVIVPRDQ TPDENEEVIV RIIGHFFASQ TAQRKIREIV QQVKQQEQKY PQGVAS.

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGF2BP2
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone 2O3W8
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IGF2BP2
Gene Accession No. Q9Y6M1
Gene Alias C330012H03Rik; Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF2BP2; IGF-II mRNA-binding protein 2; Imp2; IMP-2; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; Neilsen; p62; RGD1305614; VICKZ family member 2; VICKZ2
Gene Symbols IGF2BP2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 500-595 of human IGF2BP2/IMP2 (NP_0010072261).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10644
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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