Invitrogen™ IGFBP3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518791

Catalog No. PIPA518791

Description

This antibody is predicted to react with canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

IGFBP3 is a gene that belongs to the insulin-like growth factor binding protein (IGFBP) family. The gene encodes a protein that contains both an IGFBP domain and a thyroglobulin type-I domain. This protein is known to form a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. The complex circulates in the plasma and prolongs the half-life of IGFs while also altering their interaction with cell surface receptors. Various isoforms of the gene have been identified through alternate transcriptional splice variants. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Acid-Labile Subunit Deficiency.

Specifications

• Antigen: IGFBP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGFBP3
• Gene Alias: acid stable subunit of the 140 K IGF complex; AI649005; binding protein 29; binding protein 53; BP53; BP-53; Growth hormone dependent binding protein; growth hormone-dependent binding protein; I79_011450; IBP3; IBP-3; IGF binding protein 3; IGF-binding protein 3; IGFBP; Igfbp3; IGF-BP3; IGFBP-3; IGgfbp3; Insulin like growth factor binding protein; insulin like growth factor binding protein 3; insulin-like growth factor binding protein 3; Insulin-like growth factor binding protein 3 precursor; insulin-like growth factor-binding protein (IGF-BP3); insulin-like growth factor-binding protein 3; tcag7.703
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 3486
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P17936
• Gene Symbols: IGFBP3
• Immunogen: Synthetic peptide sequence (RYKVDYESQSTDTQN) corresponding to the internal amino acids of IGFBP3 (aa 185-200).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG