Invitrogen™ IGFBP3 Recombinant Rabbit Monoclonal Antibody (008)

Catalog No.	Quantity
PIMA530514	100 μL

Catalog No. PIMA530514

Supplier: Invitrogen™ MA530514

Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human IGFBP3.

IGFBP3 is a gene that belongs to the insulin-like growth factor binding protein (IGFBP) family. The gene encodes a protein that contains both an IGFBP domain and a thyroglobulin type-I domain. This protein is known to form a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. The complex circulates in the plasma and prolongs the half-life of IGFs while also altering their interaction with cell surface receptors. Various isoforms of the gene have been identified through alternate transcriptional splice variants. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Acid-Labile Subunit Deficiency.

Specifications

• Antigen: IGFBP3
• Applications: ELISA
• Classification: Recombinant Monoclonal
• Clone: 008
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: IGFBP3
• Gene Accession No.: P17936
• Gene Alias: acid stable subunit of the 140 K IGF complex; AI649005; binding protein 29; binding protein 53; BP53; BP-53; Growth hormone dependent binding protein; growth hormone-dependent binding protein; I79_011450; IBP3; IBP-3; IGF binding protein 3; IGF-binding protein 3; IGFBP; Igfbp3; IGF-BP3; IGFBP-3; IGgfbp3; Insulin like growth factor binding protein; insulin like growth factor binding protein 3; insulin-like growth factor binding protein 3; Insulin-like growth factor binding protein 3 precursor; insulin-like growth factor-binding protein (IGF-BP3); insulin-like growth factor-binding protein 3; tcag7.703
• Gene Symbols: IGFBP3
• Host Species: Rabbit
• Immunogen: Recombinant Human IGFBP3 Protein (Gly28-Lys291).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3486
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG