Invitrogen™ IGFBP6 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547940

Catalog No. PIPA547940

Description

In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) IGFBP-6 is observed and less than 1% cross-reactivity with rhIGFBP-1, rhIGFBP-2, rhIGFBP-3, rhIGFBP-4, and rhIGFBP-5 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6, which specifically inhibits IGF-II actions, is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.

Specifications

• Antigen: IGFBP6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGFBP6
• Gene Alias: IBP6; IBP-6; IGF binding protein 6; IGF-binding protein 6; IGFBP; IGFBP6; IGF-BP6; Igfbp-6; Insulin like growth factor binding protein; insulin like growth factor binding protein 6; insulin-like growth factor binding protein 6; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 6 PRECURSOR (IGFBP-6) (IBP-6) (IGF-BINDING PROTEIN 6); insulin-like growth factor-binding protein 6; RBP6A
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16012
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P47880
• Gene Symbols: IGFBP6
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IGFBP-6 Gly24-Gly238.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov