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PeproTech IGFBP7 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Catalog No. 500P234BT25
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50 μg
500 μg
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Catalog No. Quantity
500P234BT25 25 μg
500P234BT50 50 μg
50-271-8587 500 μg
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Catalog No. 500P234BT25 Supplier PeproTech Supplier No. 500P234BT25UG
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Description

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-BP7. Anti-Human IGF-BP7-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect hIGF-BP7 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human IGF-BP7 (500-P234) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hIGF-BP7. Western Blot: To detect hIGF-BP7 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hIGF-BP7 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P234BT-1MG will be provided as 2 x 500 μg

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGFBP7
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Biotin
Formulation PBS with no preservative
Gene IGFBP7
Gene Accession No. Q16270
Gene Alias AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
Gene Symbols IGFBP7
Host Species Rabbit
Immunogen E.coli-derived Recombinant Human IGF-BP7.
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3490
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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