Invitrogen™ IGFBP7 Recombinant Rabbit Monoclonal Antibody (003)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA530522

Catalog No. PIMA530522

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human IGFBP7.

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.

Specifications

• Antigen: IGFBP7
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q16270
• Gene Symbols: IGFBP7
• Immunogen: Recombinant Human IGFBP7 protein (Met1-Leu282).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunocytochemistry
• Clone: 003
• Conjugate: Unconjugated
• Gene: IGFBP7
• Gene Alias: AGM; angiomodulin; FSTL2; IBP7; IBP-7; IGF-binding protein 7; IGFBP; IGFBP rP1; Igfbp7; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP-rP1; Insulin like growth factor binding protein; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; Mac25; MAC25 protein; PGI2-stimulating factor; prostacyclin-stimulating factor; PSF; RAMSVPS; TAF; Tumor-derived adhesion factor
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3490
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid