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Invitrogen™ IGHA1 Monoclonal Antibody (7D12C5)
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Catalog No. PIMA531775
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100 μL
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Catalog No. Quantity
PIMA531775 100 μL
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Catalog No. PIMA531775 Supplier Invitrogen™ Supplier No. MA531775
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Description

Mouse Monoclonal Antibody

MA5-31775 has been tested in indirect ELISA.

Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGHA1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 7D12C5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene IGHA1
Gene Accession No. P01876
Gene Alias IgA1; IGHA1; IGHA2; immunoglobulin heavy constant alpha 1; immunoglobulin heavy constant alpha 2 (A2m marker)
Gene Symbols IGHA1
Host Species Mouse
Immunogen Purified recombinant fragment of human IghA1 (AA: 207-353) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3493
Target Species Human, Mouse, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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