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Invitrogen™ IGHA2 Polyclonal Antibody
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Catalog No. FEPA5144322
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100 μg
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Catalog No. Quantity
FEPA5144322 100 μg
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Catalog No. FEPA5144322 Supplier Invitrogen™ Supplier No. PA5144322
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Description

Rabbit Polyclonal Antibody

IGHA2 Polyclonal Antibody for ICC/IF, IHC (P), ELISA

The Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. The human alpha 1 and two allelic alpha 2 immunoglobulin heavy chain constant region genes contain three exons, each encoding a single constant region protein domain. Alignment of the alpha 1 and alpha 2 gene sequences reveals an unusual coupled deletion-duplication in the 5'-flanking region, which can be explained in terms of a slipped-strand mispairing model. Comparison of nucleotide sequences of the alpha 1 gene and two alleles of the alpha 2 gene indicates a localized transfer of genetic information from the 3' end of the alpha 1 gene to one of the alpha 2 alleles, probably by a gene conversion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGHA2
Applications ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 3.55 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene IGHA2
Gene Accession No. P01877
Gene Alias Ig alpha-2 chain C region; Ig alpha-2 chain C region BUT; Ig alpha-2 chain C region LAN; IGHA2Immunoglobulin heavy constant alpha 2
Gene Symbols IGHA2
Host Species Rabbit
Immunogen Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3494
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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