Invitrogen™ IGHMBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116653

Catalog No. PIPA5116653

Description

Positive Samples: HepG2, A-549, Mouse brain, Mouse testis, Rat brain Immunogen sequence: PYNLQVDLLR QSLVHRHPEL EIKSVDGFQG REKEAVILSF VRSNRKGEVG FLAEDRRINV AVTRARRHVA VICDSRTVNN HAFLKTLVEY FTQHGEVRTA FEYLDDIVPE NYSHENSQGS SHAATKPQGP ATSTRTGSQR QEGGQEAAAP ARQGRKKPAG KSLASEAPSQ PSLNGGSPEG V.

5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.

Specifications

• Antigen: IGHMBP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGHMBP2
• Gene Alias: AEP; antifreeze enhancer-binding protein; antifreeze enhancer-binding protein ortholog; ATP-dependent helicase IGHMBP2; cardiac transcription factor 1; CATF1; CMT2S; DNA-binding protein SMUBP-2; GF-1; Glial factor 1; HCSA; HMN6; Ighmbp2; immunoglobulin mu binding protein 2; immunoglobulin mu DNA binding protein 2; immunoglobulin mu-binding protein 2; immunoglobulin S mu binding protein 2; neuromuscular degeneration; nmd; p110 subunit; RIPE3b1; sma; SMARD1; Smbp2; Smbp-2; SMUBP2; ZFAND7; zinc finger, AN1-type domain 7
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20589, 29532, 3508
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.07 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P38935, P40694, Q9EQN5
• Gene Symbols: IGHMBP2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human IGHMBP2 (NP_0021712).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG