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Invitrogen™ IgM Monoclonal Antibody (II/41), eFluor™ 660, eBioscience™, Invitrogen™

Catalog No. 50579080
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50-579-080 25 μg
50-579-082 100 μg
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Catalog No. 50-579-080 Supplier Invitrogen™ Supplier No. 50579080
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Description

Rat Monoclonal Antibody

The II/41 MAb reacts with the mu heavy chain of mouse IgM. It does not react with other classes of mouse immunoglobulin including IgD, IgG or IgA. IgM is expressed intracellularly, during early stages of B lymphopoiesis, and then on the surface of more mature B cells in the bone marrow and peripheral B cells. Fluorochrome conjugated II/41 can be used as a detection secondary for mouse IgM.

Mouse IgM is an immunoglobulin M antibody that is produced by B cells in response to an antigen. It is the first antibody produced during an immune response and is the largest immunoglobulin in the serum. Mouse IgM is composed of five heavy chains and five light chains, and it is involved in complement activation and agglutination of antigens. It plays a crucial role in the innate immune response and is important for neutralizing pathogens before the adaptive immune response is fully activated. Mouse IgM is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mouse IgM
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry
Classification Monoclonal
Clone II/41
Concentration 0.2 mg/mL
Conjugate eFluor 660
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Ighm
Gene Accession No. P01872
Gene Alias AGM1; AI326478; Igh6; Igh-6; Ighm; Igh-M; Igm; immunoglobulin heavy constant mu; MU; muH; VH
Gene Symbols Ighm
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16019
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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