Invitrogen™ IGSF11 Monoclonal Antibody (OTI3A4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526622

Catalog No. PIMA526622

Description

IGSF11 Monoclonal Antibody for Western Blot, IHC (P)

Immunoglobulin superfamily member 11 (IGSF11) is a gene located on chromosome 3q13.3, encoding a transmembrane protein that belongs to the immunoglobulin superfamily. IGSF11 is known for its expression in the brain, where it plays a role in neuron-to-neuron adhesion and synaptic organization. The protein is involved in processes such as synapse formation and stabilization, impacting neural connectivity and signaling pathways. IGSF11 is also expressed in other tissues, including the gastrointestinal tract, where it can contribute to cell adhesion functions. Research has linked IGSF11 to cancer biology, as its expression is altered in various cancers, potentially influencing tumor cell adhesion and metastasis. Its role in modulating cell signaling pathways makes it an interesting target for therapeutic interventions in both neurological disorders and cancer. Current studies are focusing on its functional implications in synaptic plasticity and tumor progression, providing valuable insights into IGSF11's diverse biological roles.

Specifications

• Antigen: IGSF11
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q5DX21
• Gene Symbols: Igsf11
• Immunogen: Human recombinant protein fragment corresponding to amino acids 23-241 of IGSF11 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3A4
• Conjugate: Unconjugated
• Gene: Igsf11
• Gene Alias: 1700025L02Rik; brain and testis-specific immunoglobin superfamily protein; brain and testis-specific immunoglobulin superfamily protein; BTIGSF; Bt-IGSF; cancer/testis antigen 119; CT119; CXADR like 1; CXADRL1; Igsf11; Igsf13; Immunoglobulin superfamily member 11; immunoglobulin superfamily, member 11; immunoglobulin superfamily, member 13; V-set and immunoglobulin domain containing 3; V-set and immunoglobulin domain-containing protein 3; VSIG3
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 152404
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid