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Invitrogen™ IGSF11 Recombinant Rabbit Monoclonal Antibody (12H30L18)

Catalog No. 703178
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Catalog No. Quantity
70-317-8 100 μg
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Catalog No. 70-317-8 Supplier Invitrogen™ Supplier No. 703178
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with human and Bovine.

Immunoglobulin superfamily member 11 (IGSF11) is a gene located on chromosome 3q13.3, encoding a transmembrane protein that belongs to the immunoglobulin superfamily. IGSF11 is known for its expression in the brain, where it plays a role in neuron-to-neuron adhesion and synaptic organization. The protein is involved in processes such as synapse formation and stabilization, impacting neural connectivity and signaling pathways. IGSF11 is also expressed in other tissues, including the gastrointestinal tract, where it can contribute to cell adhesion functions. Research has linked IGSF11 to cancer biology, as its expression is altered in various cancers, potentially influencing tumor cell adhesion and metastasis. Its role in modulating cell signaling pathways makes it an interesting target for therapeutic interventions in both neurological disorders and cancer. Current studies are focusing on its functional implications in synaptic plasticity and tumor progression, providing valuable insights into IGSF11's diverse biological roles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGSF11
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 12H30L18
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2-7.4
Gene Igsf11
Gene Accession No. P0C673, Q5DX21, Q5U2P2
Gene Alias 1700025L02Rik; brain and testis-specific immunoglobin superfamily protein; brain and testis-specific immunoglobulin superfamily protein; BTIGSF; Bt-IGSF; cancer/testis antigen 119; CT119; CXADR like 1; CXADRL1; Igsf11; Igsf13; Immunoglobulin superfamily member 11; immunoglobulin superfamily, member 11; immunoglobulin superfamily, member 13; V-set and immunoglobulin domain containing 3; V-set and immunoglobulin domain-containing protein 3; VSIG3
Gene Symbols Igsf11
Host Species Rabbit
Immunogen Protein corresponding to human IGSF11 (aa263-aa431,aa23-aa241).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 152404, 207683, 303926
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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