Invitrogen™ IGSF8 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547450

Catalog No. PIPA547450

Description

In direct ELISAs, approximately 15% cross-reactivity with recombinant human IGSF8 is observed and less than 1% cross-reactivity with recombinant mouse IGSF4 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Specifications

• Antigen: IGSF8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGSF8
• Gene Alias: AA033172; AU041109; CD316; CD81 partner 3; CD81P3; ESTM34; EWI2; EWI-2; Glu-Trp-Ile EWI motif-containing protein 2; IGSF8; Immunoglobulin superfamily member 8; immunoglobulin superfamily, member 8; Kct4; KCT-4; Keratinocyte-associated transmembrane protein 4; keratinocytes-associated transmembrane protein 4; LIR-D1; PG regulatory-like protein; PGRL; Prostaglandin regulatory-like protein; R75384
• Host Species: Goat
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140559, 304979, 93185
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8R366, Q969P0
• Gene Symbols: IGSF8
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IGSF8/CD316 Ala25-Thr577.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG