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Invitrogen™ IKAP Polyclonal Antibody
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Catalog No. PIPA587654
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100 μL
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PIPA587654 100 μL
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Catalog No. PIPA587654 Supplier Invitrogen™ Supplier No. PA587654
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRLVYKYNRL DIIETNVKPS ILEAQKNYMA FLDSQTATFS RHKKRLLVVR ELKEQAQQAG LDDEVPHGQE SDLFSETSSV VSGSEMSGKY SHSNSRISAR SSKNRRKAER KKHSLKEGSP LEDLALLEAL SEVVQNTENL KDEVYHILKV LFLFEFDEQG RELQKAFEDT LQLMERSLPE IWTLTYQQNS ATPVLGPNST ANSIMASYQQ QKTSVPVLDA ELFIPPKINR RTQWKLSLLD; Positive Samples: HeLa, HepG2, U-251MG, HL-60, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Nucleus.

The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IKAP
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.94 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ELP1
Gene Accession No. O95163, Q7TT37, Q8VHU4
Gene Alias 3110040G09Rik; 6030413P05; C78473; DKFZp781H1425; DYS; elongator acetyltransferase complex subunit 1; elongator complex protein 1; Elp1; FD; FLJ12497; IKAP; IkappaB kinase complex-associated protein; IKBKAP; IKI3; IKK complex-associated protein; IKK-complex-associated protein IKAP; inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein; inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein; p150; RP11-3J11.4; TOT1
Gene Symbols ELP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1093-1332 of human IKBKAP (NP_0036312).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140934, 230233, 8518
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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