Invitrogen™ IKAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587654

Catalog No. PIPA587654

Description

Immunogen sequence: LRLVYKYNRL DIIETNVKPS ILEAQKNYMA FLDSQTATFS RHKKRLLVVR ELKEQAQQAG LDDEVPHGQE SDLFSETSSV VSGSEMSGKY SHSNSRISAR SSKNRRKAER KKHSLKEGSP LEDLALLEAL SEVVQNTENL KDEVYHILKV LFLFEFDEQG RELQKAFEDT LQLMERSLPE IWTLTYQQNS ATPVLGPNST ANSIMASYQQ QKTSVPVLDA ELFIPPKINR RTQWKLSLLD; Positive Samples: HeLa, HepG2, U-251MG, HL-60, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Nucleus.

The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.

Specifications

• Antigen: IKAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ELP1
• Gene Alias: 3110040G09Rik; 6030413P05; C78473; DKFZp781H1425; DYS; elongator acetyltransferase complex subunit 1; elongator complex protein 1; Elp1; FD; FLJ12497; IKAP; IkappaB kinase complex-associated protein; IKBKAP; IKI3; IKK complex-associated protein; IKK-complex-associated protein IKAP; inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein; inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein; p150; RP11-3J11.4; TOT1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140934, 230233, 8518
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.94 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O95163, Q7TT37, Q8VHU4
• Gene Symbols: ELP1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1093-1332 of human IKBKAP (NP_0036312).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG