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Invitrogen™ IkB zeta Polyclonal Antibody
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Catalog No. PIPA517139
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100 μL
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PIPA517139 100 μL
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Catalog No. PIPA517139 Supplier Invitrogen™ Supplier No. PA517139
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

I-kappa-B-zeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein that is highly homologous to the IkappaB family member Bcl-3. Transcription of IkappaBzeta is upregulated by stimulation with TLR ligands, IL-1 and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65 and recombinant IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IkB zeta
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 86 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.15M NaCl, 50% glycerol, 100 μg/mL BSA and no preservative; pH 7.5
Gene NFKBIZ
Gene Accession No. Q9BYH8
Gene Alias AA408868; FLJ30225; FLJ34463; Ikappa B-zeta variant 3; ikappaBzeta; I-kappa-B-zeta; IkappaB-zeta; IKBZ; ikB-zeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; molecule possessing ankyrin repeats induced by lipopolysaccharide; molecule possessing ankyrin-repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKB inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; OTTHUMP00000214340; RGD1310834
Gene Symbols NFKBIZ
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues at the amino terminus of human IkB zeta.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64332
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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