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Invitrogen™ IKBIP Polyclonal Antibody
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Catalog No. PIPA565219
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100 μL
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PIPA565219 100 μL
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Catalog No. PIPA565219 Supplier Invitrogen™ Supplier No. PA565219
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DSTLRNIRTVK RQEEEDLLRV EEQLGSDTKA IEKLEEEQHA LFARDEDLTN KLSDYEPKVE ECKTHLPTIE SAI Highest antigen sequence identity to the following orthologs - mouse 85%, rat 84%.

IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IKBIP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IKBIP
Gene Accession No. Q70UQ0
Gene Alias 1200009F10Rik; 1700023M03Rik; D18354; I kappa B kinase interacting protein; i kappa-B kinase interacting protein; i kappa-B kinase-interacting protein; Ikbip; IKBKB interacting protein; IKBKB-interacting protein; Ikip; IKK interacting protein; IKK-interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein
Gene Symbols IKBIP
Host Species Rabbit
Immunogen Recombinant Human IKBIP. Recombinant protein control fragment (Product #RP-104692).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 121457
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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