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IKIP Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501729564 Shop All Proteintech Group Inc Products
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50-172-9564 150 μL
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Catalog No. 50-172-9564 Supplier Proteintech Group Inc Supplier No. 145891AP150UL
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Rabbit Polyclonal Antibody

IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.

Specifications

Antigen IKIP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IKBIP
Gene Accession No. Q70UQ0, Q9DBZ1
Gene Alias IKBIP, IKBKB interacting protein, IKIP, IKK interacting protein
Gene Symbols Ikbip
Host Species Rabbit
Immunogen IKIP Fusion Protein Ag6119
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 121457, 67454
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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