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  5. Tocris Bioscience™ IKK 16

Tocris Bioscience™ IKK 16
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Catalog No. 253910
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective inhibitor of IKK

Selective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). Inhibits TNF-α-stimulated IκB degradation and expression of adhesion molecules E-selectin, ICAM and VCAM (IC50 values are 1.0, 0.5, 0.3 and 0.3 μM respectively). Inhibits LPS-induced TNF-α release in vivo and neutrophil extravasion in thioglycollate-induced peritonitis.

Chemical Identifiers

CAS 1186195-62-9
Molecular Formula C28H30ClN5OS

Specifications

Quantity 10 mg
Formula Weight 520.09
Purity >98%
Molecular Weight (g/mol) 520.092
Chemical Name or Material IKK 16

Safety and Handling

Recommended Storage Desiccate at -20°C
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