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Tocris Bioscience™ IKK 16
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Catalog No. 253950
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50 mg
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Catalog No. Quantity
25-395-0 50 mg
25-391-0 10 mg
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Catalog No. 25-395-0 Supplier Tocris Bioscience™ Supplier No. 2539/50
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Description

Selective inhibitor of IKK

Selective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). Inhibits TNF-α-stimulated IκB degradation and expression of adhesion molecules E-selectin, ICAM and VCAM (IC50 values are 1.0, 0.5, 0.3 and 0.3 μM respectively). Inhibits LPS-induced TNF-α release in vivo and neutrophil extravasion in thioglycollate-induced peritonitis.

Chemical Identifiers

CAS 1186195-62-9
Molecular Formula C28H30ClN5OS

Specifications

Quantity 50 mg
Formula Weight 520.09
Purity >98%
Molecular Weight (g/mol) 520.092
Chemical Name or Material IKK 16

Safety and Handling

Recommended Storage Desiccate at -20°C
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