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Invitrogen™ IKK alpha Polyclonal Antibody
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Catalog No. PIPA585745
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100 μL
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PIPA585745 100 μL
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Catalog No. PIPA585745 Supplier Invitrogen™ Supplier No. PA585745
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Positive Control: HeLa, Jurkat, Raji, HCI-H929, K562, THP-1, HL-60. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. IKK alpha along with IKK beta and a regulatory protein NEMO (IKK gamma) phosphorylates IkB proteins which targets the later for ubiquitin mediated degradation. It is involved with several cellular processes with extensive studies on its role in inflammation and cell survival.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IKK alpha
Applications Western Blot
Classification Polyclonal
Concentration 1.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene CHUK
Gene Accession No. O15111
Gene Alias AI256658; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; FLJ40509; I kappa B kinase 1; i kappa-B kinase alpha; ikappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IkB kinase-alpha; ikBKA; IKBKB; IKK alpha; IKK1; IKK2; Ikka; IKK-A; IKK-a kinase; IKK-alpha; IKKB; IKK-B; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase alpha; TCF16; TCF-16; Transcription factor 16
Gene Symbols CHUK
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IKK alpha. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1147
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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