IKZF3 Monoclonal Antibody (OTI1E1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804235

Catalog No. 50-168-0153

Description

IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Specifications

• Antigen: IKZF3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9UKT9
• Gene Symbols: IKZF3
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-301 of human IKZF3 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1E1
• Conjugate: Unconjugated
• Gene: IKZF3
• Gene Alias: AIO, AIOLOS, ZNFN1A3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22806
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid