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Invitrogen™ IKZF3 Recombinant Rabbit Monoclonal Antibody (4U7F9)
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Catalog No. PIMA542889
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100 μL
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PIMA542889 100 μL
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Catalog No. PIMA542889 Supplier Invitrogen™ Supplier No. MA542889
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: Raji, Mouse spleen, Mouse thymus, Rat lung. Immunogen sequence: IYQQNHMVLS RARNGMPLLK EVPRSYELLK PPPICPRDSV KVINKEGEVM DVYRCDHCRV LFLDYVMFTI HMGCHGFRDP FECNMCGYRS HDRYEFSSHI ARGEHRALLK.

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IKZF3
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 4U7F9
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Ikzf3
Gene Accession No. O08900, Q9UKT9
Gene Alias 5830411O07Rik; AIO; AIOLOS; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); ikaros family zinc finger protein 3; Ikzf3; Zfpn1a3; zinc finger DNA binding protein Aiolos; zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); Znfn1a3
Gene Symbols Ikzf3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 400-509 of human IKZF3 (Q9UKT9).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22780, 22806, 303511
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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