IL-1 Receptor Type I Polyclonal Antibody, Rockland™

Catalog No.	Quantity
50-199-0229	100 μL
50-199-0230	25 μL
50-199-0228	1 mL

Catalog No. 50-199-0229 Supplier Rockland Immunochemicals Supplier No. 1094013040100

Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. The antiserum is directed against the extracellular domain of the human IL-1R type I, but precipitates the intact receptor expressed on human cells. In general, this antibody also detects primate IL-1RI. The antibody does not recognize human IL-1, IL-1Ra or IL-1R type II. In ELISA formats and other immunoreactive assays, this antibody will detect the extracellular domain of the IL-1R type I (also called soluble IL-1R type I or decoy receptor) found in human body fluids, particularly in the circulation, urine and supernatants of cells and synovial fluid.

The IL-1 system includes two agonists (IL-1 and IL-1), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.

Specifications

• Antigen: IL-1 Receptor Type I
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 84 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M sodium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene: Il1r1
• Gene Accession No.: P14778
• Gene Alias: antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; CD121b; D2S1473; IL-1 receptor alpha chain; IL1R; IL1R1; Il-1r1; IL-1R-1; Il1r-1; Il1ra; IL-1R-alpha; IL1RT1; IL-1RT1; IL-1RT-1; IL-iR; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor alpha, type I; interleukin 1 receptor type 1; interleukin 1 receptor, type I; Interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form; Interleukin-1 receptor type I; mIL-1R1; p80; sIL-1R1
• Gene Symbols: Il1r1
• Host Species: Rabbit
• Immunogen: IL-1 Receptor Type I Antibody was prepared by repeated immunizations with recombinant human IL-1R type I.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3554
• Target Species: Human, Non-human Primate
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid